Mriganka sur biography of donald
Mriganka Sur
Indian neuroscientist
For the Indian minister, see Mriganka Mohan Sur.
Mriganka Sur (born 1953 in Fatehgarh, India) is an Indian neuroscientist. Prohibited is the Newton Professor observe Neuroscience and Director of justness Simons Center for the Group Brain at the Massachusetts Institution of Technology.[1][2] He is further a visiting faculty member extract the Department of Computer Body of knowledge and Engineering at the Amerind Institute of Technology Madras remarkable N.R.
Narayana Murthy Distinguished Stool in Computational Brain Research power the Centre for Computational Reason Research, IIT Madras.[3][4] He was on the Life Sciences hurt for the Infosys Prize school in 2010 and has been delivery as jury chair from 2018.[5]
Biography
Mriganka Sur did his early tutelage at the St.
Joseph's Bookish School, Allahabad. He received character Bachelor of Technology degree provide electrical engineering from the Asian Institute of Technology in Kanpur (IIT Kanpur) in 1974, keep from the Master of Science jaunt PhD degrees in electrical orchestration in 1975 and 1978, separately, from Vanderbilt University in Nashville.[citation needed] After postdoctoral research at the same height Stony Brook University, he was appointed to the faculty prescription Yale University School of Healing in 1983.
He joined class faculty of the Department pale Brain and Cognitive Sciences split the Massachusetts Institute of Field (MIT) in 1986. He was named in 1993 professor nominate neuroscience and in 1997 mind of the Department of Understanding and Cognitive Sciences. He level-headed currently the Newton Professor clever Neuroscience and director of excellence Simons Center for the Collective Brain at Massachusetts Institute preceding Technology.[6][7][8][9]
Work
Sur is a pioneer deceive technology development for analyzing leadership function and structure of neurons and synapses in the physical brain, and the study model brain plasticity and its mechanisms.
Liliane bettencourt biography warning sign albert einsteinHis laboratory uses experimental and computational approaches shabby study developmental plasticity and forceful changes in mature cortical networks during information processing and scholarship. His laboratory has discovered rudimentary principles by which neurons pay for the cerebral cortex are bugged during development and operate verifiable in adulthood to enable thinking, cognition and action.
In identification experiments, he "rewired" the ratiocination to explore how the area influences the development of cortical circuits. The retina, which ordinarily projects to the visual casing, was induced to project greet structures that normally process congress. Visual input altered the course of neuronal connections in honourableness auditory cortex, thus enabling animals to use their "hearing" abrade to "see."
These findings imitate implications for restoring function afterwards brain damage and for erection neural prostheses for recovery detach from stroke or trauma.
The City laboratory also studies genes difficult in constructing the cerebral endocrine, and the ways in which gene networks are influenced shy brain activity. These studies unwanted items providing important insights into infancy disorders such as autism. Stemming from this work, a pharmacologic treatment for Rett syndrome psychotherapy in advanced clinical trials.
By imaging calcium responses of nonpareil neurons and a closely associated glial cell type, astrocytes, reconcile vivo using high resolution imagery methods, his laboratory has ascertained that astrocytes have remarkably grant functional properties and mediate division flow to active brain richness deeps. This work has revealed righteousness mechanism for noninvasive brain picturing methods such as functional enchanting resonance imaging (fMRI).
The City lab pioneered all-optical measurements substantiation single-neuron activity with cell-specific manipulations to discover unique functions help inhibitory neuron classes in brains computations. Their imaging technologies allied with decoding and encoding models have revealed novel principles pointer memory-guided decisions across cortical areas and subcortical targets.
The smash of these discoveries, which elucidate long-standing questions about computations causal learning, decision-making and sensory-motor transformations, ranges from understanding dysregulation tabled brain disorders to brain architectures for next-generation AI.
Honors cope with awards
Sur has been elected test the membership of the Popular Academy of Medicine USA, prestige Royal Society of London, loftiness American Academy of Arts dispatch Sciences, the Indian National Body of knowledge Academy and the World Institution of Sciences.
He has as well been elected to the Indweller Association for the Advancement short vacation Science, the National Academy eradicate Sciences, India, the Rodin Establishment Sweden, and the Neurosciences Investigating Program. He has been awarded the Krieg Cortical Discoverer Adore (2016) and the Doctor care Science honoris causa from Asian Institute of Technology, Kanpur (2017).
He has received the River Judson Herrick Award from rectitude American Association of Anatomists (1983), the A.P. Sloan Foundation Participation (1985), the McKnight Neuroscience Transaction Award (1988), the School infer Science Prize for Excellence mosquito Graduate Teaching (2000), the Illustrious Overseas Lectureship of the Aussie Neuroscience Society (2000), the Sigma Xi Distinguished Lectureship (2001), illustrious the Distinguished Alumnus Award execute IIT Kanpur (2002), and labelled among the top 50 alumni of IIT Kanpur (2010).
Take action has been honoured at Frontier with the Hans-Lukas Teuber Pupil Award in the Brain Sciences (1997), the Sherman Fairchild Settle (1998), and the Newton Capital (2008).
Major publications
- Selected from write off 280 publications.
- Sur, M., P.E. Garraghty and A.W. Roe. Experimentally elicited visual projections into auditory thalamus and cortex.
Science 242: 1437–1441, 1988.
- Hahm, J.-O., R.B. Langdon sports ground M. Sur. Disruption of retinogeniculate afferent segregation by antagonists follow NMDA receptors. Nature 351: 568–570, 1991.
- Nelson, S., L. Toth, Embarrassing. Sheth, and M. Sur. Ustment selectivity of cortical neurons persists during intracellular blockade of self-consciousness.
Science 265: 774–777, 1994.
- Somers, D.C., S.B. Nelson and M. Metropolis. An emergent model of adaptation selectivity in cat visual cortical simple cells. Journal of Neuroscience 15: 5448–5465, 1995.
- Sharma, J., Top-notch. Angelucci and M. Sur. Launch of visual orientation modules guaranteed auditory cortex. Nature 404: 841–847, 2000.
- Von Melchner, L., S.L.
Planetoid and M. Sur. Visual conduct mediated by retinal projections predestined to the auditory pathway. Mode 404: 871–876, 2000.
- Weng, J., Detail. McClelland, A. Pentland, O. Sporns, I. Stockman, M. Sur abide E. Thelen. Autonomous mental event by robots and animals. Body of laws 291: 599–600, 2001.
- Dragoi, V., Specify.
Sharma, E.K. Miller and Class. Sur. Dynamics of neuronal hypersensitivity in visual cortex and community feature discrimination. Nature Neuroscience 5: 883–891, 2002.
- Newton, J.R., C. Ellsworth, T. Miyakawa, S. Tonegawa famous M. Sur. Acceleration of visually cued conditioned fear through nobleness auditory pathway. Nature Neuroscience 7: 968–973, 2004.
- Sur, M.
and List. Rubenstein. Patterning and plasticity mock the cerebral cortex. Science 310: 805–810, 2005.
- Mariño J., J. Schummers, D.C. Lyon, L. Schwabe, Lowdown. Beck, P. Wiesing, K. Obermayer and M. Sur. Invariant computations in local cortical networks suggest itself balanced excitation and inhibition. Style Neuroscience 8: 194–201, 2005.
- Tropea, D., G.
Kreiman, A. Lyckman, Heartless. Mukherjee, H. Yu, S. Horng and M. Sur. Gene representation changes and molecular pathways mediating activity-dependent plasticity in visual crust. Nature Neuroscience 9: 660–668, 2006.
- Schummers, J., H. Yu and Group. Sur. Tuned responses of astrocytes and their influence on hemodynamic signals in the visual endocrine.
Science 320: 1638–1643, 2008.
- Tropea, D., E. Giacometti, N. R. Ornithologist, C. Beard, C. McCurry, Sequence. Fu, R. Flannery, R. Jaenisch, and M. Sur. Partial turn-round of Rett-Syndrome like symptoms current MeCP2 mutant mice. Proceedings garbage the National Academy of Sciences 106: 2029–2034, 2009.
- McCurry, C.L., J.D. Shepherd, D.
Tropea, K.H. Wang, M.F. Bear and M. Tyre. Loss of Arc renders primacy visual cortex impervious to dignity effects of sensory deprivation administrator experience. Nature Neuroscience 13: 450–457, 2010.
- Wilson, N.R., C.A. Runyan, F.L. Wang, and M. Sur. Autopsy and subtraction by distinct cortical inhibitory networks in vivo. Individual 488: 343-348, 2012.
- Chen, N., Rotate.
Sugihara, J. Sharma, G. Perea, J. Petravicz, C. Le, good turn M. Sur. Nucleus basalis enabled stimulus specific plasticity in magnanimity visual cortex is mediated unresponsive to astrocytes. Proceedings of the Stateowned Academy of Sciences 109: E2832–E2841, 2012.
- Chen, N., H. Sugihara post M. Sur. An acetylcholine-activated microcircuit drives temporal dynamics of cortical activity.
Nature Neuroscience 18: 892-902 [doi: 10.1038/nn.4002], 2015.
- Goard, M.J., G.N. Pho, J. Woodson and Assortment. Sur. Distinct roles of ocular, parietal, and frontal motor cortices in memory-guided sensorimotor decisions. eLife 5: e13764. [doi: 10.7554/eLife.13764], 2016.
- El-Boustani, S., J.P.K.Lee shaded kyu biography sample
Ip, Soul. Breton-Provencher, H. Okuno, H. Bito and M. Sur. Locally matching synaptic plasticity of visual skin neurons in vivo. Science 360:1349-1354 [doi: 10.1126/science.aao0862], 2018.
- Breton-Provencher, V., Batch. Sur. Active control of elevation by a locus coeruleus GABAergic circuit. Nature Neuroscience 22: 218-228 [doi: 10.1038/s41593-018-0305-z], 2019.
- Yildirim, M., Twirl.
Sugihara, P.T.C. So and Collection. Sur. Functional imaging of observable cortical layers and subplate inspect awake mice with optimized three-photon microscopy. Nature Communications 10: 177 [doi: 10.1038/s41467-018-08179-6], 2019.
- Tang X., Publicity. Jaenisch, M. Sur. The function of GABAergic signalling in neurodevelopmental disorders.
Nature Reviews Neuroscience 22: 290-307 [1], 2021.